EQS-Adhoc: Pentixapharm Holding AG: Pentixapharm significantly reduces projected loss for financial year 2025
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EQS-Ad-hoc: Pentixapharm Holding AG / Key word(s): Annual Results Ad-hoc Disclosure of Inside Information Pursuant to Article 17 Regulation (EU)
Pentixapharm significantly reduces projected loss for financial year 2025
Berlin, Germany, November 6, 2025 – Pentixapharm Holding AG (Frankfurt Prime Standard: PTP), an advanced clinical-stage biotech developing radiopharmaceuticals, announces that its projected consolidated loss for the financial year 2025, based on an updated projection, will be significantly lower than previously anticipated.
The company now forecasts an annual loss of approximately €18 million instead of the previously expected €23.5 million. The forecasts for the separate financial statements of Pentixapharm Holding AG as well as the expected cash reach until the first quarter of 2027 remain unchanged.
The revised forecast reflects the realignment of the clinical development programs initiated in May 2025. In particular, the earlier-than-planned termination of the slow-recruiting diagnostic study in marginal zone lymphoma and optimized study design have lowered clinical spending more significantly than initially expected. With the sharpened focus on the clinically most value driving programs implemented in October 2025, the company is continuing to execute on its optimization course.
About Pentixapharm Pentixapharm is an advanced clinical-stage biotech expanding the boundaries of radiopharmaceuticals. Headquartered in Berlin, Germany, the company develops precision diagnostics and therapeutics in oncology and cardiology to transform patient care. Its clinical pipeline is anchored by CXCR4-targeted PET-CT programs, including a Phase 3-ready candidate for the improved diagnosis of hypertensive patients with primary aldosteronism, which is intended to enable targeted treatment of the underlying causes of hypertension. CXCR4-based developments also include pioneering therapeutic programs in hematological cancers. Furthermore, Pentixapharm is advancing a next-generation antibody platform targeting CD24, an emerging immune-checkpoint marker over-expressed in multiple hard-to-treat cancers. Complemented by CXCR4 and CD24 intellectual property protection and a reliable isotope supply chain, Pentixapharm is poised to deliver meaningful patient benefit and sustainable growth in one of the fastest-growing areas of precision medicine.
Pentixapharm Investor and Media Contact End of Inside Information
06-Nov-2025 CET/CEST The EQS Distribution Services include Regulatory Announcements, Financial/Corporate News and Press Releases. |
| Language: | English |
| Company: | Pentixapharm Holding AG |
| Robert-Rössle-Straße 10 | |
| 13125 Berlin | |
| Germany | |
| E-mail: | info@pentixapharm.com |
| Internet: | https://www.pentixapharm.com/ |
| ISIN: | DE000A40AEG0 |
| WKN: | A40AEG |
| Listed: | Regulated Market in Frankfurt (Prime Standard); Regulated Unofficial Market in Berlin, Dusseldorf, Hamburg, Hanover, Munich, Stuttgart, Tradegate Exchange |
| EQS News ID: | 2225518 |
| End of Announcement | EQS News Service |
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2225518 06-Nov-2025 CET/CEST
Boersengefluester.de (BGFL) provides an overview of the key figures on sales, earnings, cash flow and dividends to help you better assess the fundamental development of the respective companies. All information is entered manually in our database - the source is the respective annual reports. All estimates for future figures are provided by BGFL.
| The most important financial data at a glance | ||||||||
| 2019 | 2020 | 2021 | 2022 | 2023 | 2024 | 2025e | ||
| Sales1 | 0,00 | 0,07 | 0,06 | 0,05 | 1,77 | 0,12 | 0,00 | |
| EBITDA1,2 | 0,00 | -1,85 | -4,07 | -5,89 | -10,62 | 2,07 | 0,00 | |
| EBITDA-Margin3 | 0,00 | -2.642,86 | -6.783,33 | -11.780,00 | -600,00 | 1.725,00 | 0,00 | |
| EBIT1,4 | 0,00 | -1,92 | -4,18 | -6,00 | -10,76 | -16,97 | 0,00 | |
| EBIT-Margin5 | 0,00 | -2.742,86 | -6.966,67 | -12.000,00 | -607,91 | -14.141,67 | 0,00 | |
| Net Profit (Loss)1 | 0,00 | -1,92 | -4,18 | -1,96 | -7,64 | -12,84 | -18,00 | |
| Net-Margin6 | 0,00 | -2.742,86 | -6.966,67 | -3.920,00 | -431,64 | -10.700,00 | 0,00 | |
| Cashflow1,7 | 0,00 | -1,85 | -2,49 | -2,20 | 2,13 | -4,33 | 0,00 | |
| Earnings per share8 | 0,00 | -0,08 | -0,17 | -0,08 | -0,30 | -0,52 | -0,73 | |
| Dividend per share8 | 0,00 | 0,00 | 0,00 | 0,00 | 0,00 | 0,00 | 0,00 | |
1 in Mio. Euro; 2 EBITDA = Earnings before interest, taxes, depreciation and amortisation; 3 EBITDA in relation to sales; 4 EBIT = Earnings before interest and taxes; 5 EBIT in relation to sales; 6 Net profit (-loss) in relation to sales; 7 Cashflow from operations; 8 in Euro; Source: boersengefluester.de
Auditor: Forvis Mazars
All relevant valuation ratios, dates and other investor information on your share at a glance. Good to know: All data comes from boersengefluester.de and is updated daily. This means you are always up to date. You can get brief explanations of the key figures by moving the cursor or mouse over the relevant field.
| INVESTOR-INFORMATION | ||||||
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| Pentixapharm Holding | ||||||
| WKN | ISIN | Legal Type | Marketcap | IPO | Recommendation | Plus Code |
| A40AEG | DE000A40AEG0 | AG | 37,19 Mio € | 03.10.2024 | Kaufen | 8FXFRW2H+CF |
| PE 2026e | PE 10Y-Ø | BGFL-Ratio | Shiller-PE | PB | PCF | KUV |
| -1,00 | 0,00 | 0,00 | -1,67 | 1,01 | -8,59 | 315,19 |
|
Dividend '2023 in € |
Dividend '2024 in € |
Dividend '2025e in € |
Div.-Yield '2025e in % |
| 0,00 | 0,00 | 0,00 | 0,00% |
| Annual General Meeting | Q1-figures | Q2-figures | Q3-figures | Annual press conference |
| 27.05.2025 | 08.05.2025 | 06.08.2025 | 12.11.2025 | 15.04.2025 |
| Distance 60-days-line | Distance 200-days-line | Performance YtD | Performance 52 weeks | IPO |
| -8,54% | -34,01% | -49,15% | -51,30% | -70,59% |
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